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11-deoxy-11-methylene Prostaglandin D2

品牌：Cayman

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说明书

折扣/货期

货号：12410-1 mg	规格：1 mg	目录价：￥994
货号：12410-10 mg	规格：10 mg	目录价：￥7756
货号：12410-5 mg	规格：5 mg	目录价：￥4382

产品详情

产品名称:

11-deoxy-11-methylene Prostaglandin D2

别名:

11-deoxy-11-methylene PGD2

产品描述:

Prostaglandin D2 (PGD2; Item No. 12010) is one of the five primary enzymatic prostaglandins derived directly from PGH2 (Item No. 17020). PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, leukocyte-type PGD synthase.{9588} PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. 11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin.{7894} However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets, a DP1 receptor assay.{11175} The CRTH2-receptor actions of 11-deoxy-11-methylene PGD2 are not yet reported.

保存温度:

-20

运输温度:

-20

预期分子量:

350.5

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥98%