货号:16520-1 mg | 规格:1 mg | 目录价:¥1960 |
货号:16520-10 mg | 规格:10 mg | 目录价:¥15498 |
货号:16520-5 mg | 规格:5 mg | 目录价:¥8736 |
产品详情
产品名称:
11β-Prostaglandin F2α
别名:
11-epi PGF2α|11β-PGF2α|9α,11β-PGF2α
产品描述:
11β-Prostaglandin F2α (11β-PGF2α) is the primary metabolite of PGD2 (Item No. 12010).{57057} It is formed from PGD2 via the NADPH-dependent aldo-keto reductase PGF synthase (PGFS; Item No. 10007940) in the liver or lung.{57058} 11β-PGF2α induces contraction of isolated cat iris sphincter, which endogenously expresses high levels of PGF2α (FP) receptors, with an EC50 value of 0.045 µM.{57057} It also induces contraction of isolated human bronchial smooth muscle when used at concentrations ranging from 0.1 to 30 µM.{1756} 11β-PGF2α (0.1 and 1 µM) induces phosphorylation of ERK and CREB, as well as increases the viability of MCF-7 breast cancer cells stably expressing the FP receptor when used at concentrations of 0.1 and 1 µM.{57059}
保存温度:
-20
运输温度:
-20
预期分子量:
354.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
38432-87-0
分子式:
C20H34O5
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