11β-Prostaglandin F2α-d4-前列腺素-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳公海赌赌船官网登录网址科技有限公司

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11β-Prostaglandin F2α-d4

品牌：Cayman

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说明书

折扣/货期

货号：10008989-100 µg	规格：100 µg	目录价：￥2212
货号：10008989-50 µg	规格：50 µg	目录价：￥1190
货号：10008989-500 µg	规格：500 µg	目录价：￥5236

产品详情

产品名称:

11β-Prostaglandin F2α-d4

别名:

11-epi PGF2α-d4|11β-PGF2α-d4|9α,11β-PGF2α-d4

产品描述:

11β-Prostaglandin F2α-d4 (11β-PGF2α-d4) is intended for use as an internal standard for the quantification of 11β-PGF2α (Item No. 16520) by GC- or LC-MS. 11β-PGF2α is the primary metabolite of PGD2 (Item No. 12010).{57057} It is formed from PGD2 via the NADPH-dependent aldo-keto reductase PGF synthase (PGFS; Item No. 10007940) in the liver or lung.{57058} 11β-PGF2α induces contraction of isolated cat iris sphincter, which endogenously expresses high levels of PGF2α (FP) receptors, with an EC50 value of 0.045 µM.{57057} It also induces contraction of isolated human bronchial smooth muscle when used at concentrations ranging from 0.1 to 30 µM.{1756} 11β-PGF2α (0.1 and 1 µM) induces phosphorylation of ERK and CREB, as well as increases the viability of MCF-7 breast cancer cells stably expressing the FP receptor when used at concentrations of 0.1 and 1 µM.{57059}

保存温度:

-20

运输温度:

-20

预期分子量:

358.5

产品形式:

A solution in ethanol

有效期:

365

纯度:

≥99% deuterated forms (d1-d4)