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    13,14-dihydro-16,16-difluoro Prostaglandin E1
    货号:9000405-1 mg 规格:1 mg 目录价:¥5194
    货号:9000405-100 µg 规格:100 µg 目录价:¥672
    货号:9000405-5 mg 规格:5 mg 目录价:¥22582
    货号:9000405-500 µg 规格:500 µg 目录价:¥2940
    产品详情
    产品名称:
    13,14-dihydro-16,16-difluoro Prostaglandin E1
    别名:
    15-hydroxy Lubiprostone
    产品描述:
    Prostaglandin E1 (PGE1) is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway. PGE1 inhibits platelet aggregation (IC50 = 40 nM){960,4165} and increases vasodilation. 13,14-dihydro-16,16-difluoro PGE1 is an analog of PGE1. 13,14-dihydro PGE1 is a biologically active metabolite of PGE1, inhibiting platelet aggregation with comparable potency to the parent compound.{2126,4165} The addition of two electron-withdrawing fluorine atoms, which should stabilize the molecule against hydrolytic cleavage, may be expected to delay degradation in vivo.{17623}
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    392.5
    产品形式:
    A solution in methyl acetate
    有效期:
    730
    纯度:
    ≥98%
    CAS号:
    475992-30-4
    分子式:
    C20H34F2O5
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