15-deoxy-Δ12,14-Prostaglandin D2-d4-前列腺素-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳公海赌赌船官网登录网址科技有限公司

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15-deoxy-Δ12,14-Prostaglandin D2-d4

品牌：Cayman

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说明书

折扣/货期

货号：19343

规格：100 µg

目录价：￥4914

产品详情

产品名称:

15-deoxy-Δ12,14-Prostaglandin D2-d4

别名:

15-deoxy-Δ12,14-PGD2-d4

产品描述:

15-deoxy-Δ12,14-Prostaglandin D2-d4 (15-deoxy-Δ12,14-PGD2-d4) is an internal standard for the quantification of 15-deoxy-Δ12,14-PGD2 (Item No. 12700) by GC- or LC-MS. 15-deoxy-Δ12,14-PGD2 is a metabolite of PGD2 (Item No. 12010).{11797} It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki = 50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils (EC50 = 8 nM).{11399,11055} It also stimulates the recruitment of steroid receptor coactivator-1 (SRC-1) to peroxisome proliferator-activated receptor γ (PPARγ) and induces PPARγ-mediated transcription in a reporter assay when used at a concentration of 5 µM.{11797} 15-deoxy-Δ12,14-PGD2 is cytotoxic to L1210 murine leukemia cells (IC50 = 0.3 µg/ml).{1424} It inhibits ADP-induced platelet aggregation (IC50 = 320 ng/ml) less potently than PGD2.{1139}

保存温度:

-20

运输温度:

-20

预期分子量:

338.5

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥99% deuterated forms (d1-d4)