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15-deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester

品牌：Cayman

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说明书

折扣/货期

货号：10010132-1 mg	规格：1 mg	目录价：￥5320
货号：10010132-100 µg	规格：100 µg	目录价：￥686
货号：10010132-500 µg	规格：500 µg	目录价：￥3024

产品详情

产品名称:

15-deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester

别名:

15-deoxy-Δ12,14-PGJ2-2-glyceryl ester

产品描述:

15-deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester (15-deoxy-Δ12,14-PGJ2-2-glyceryl ester) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 µM in a murine chimera system.{1428,1424} 15-deoxy-Δ12,14-PGJ2-2-glyceryl ester is more potent than PGD2, Δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 value for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.{1428} PG glycerol esters are generated by the action of cyclooxygenase-2 on the endocannabinoid 2-arachidonyl glycerol.{11045} The biosesynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. While the stability and metabolism of these PG products has been investigated,{10555} little is known about their intrinsic biological activity.

保存温度:

-80

运输温度:

-80

预期分子量:

390.5

产品形式:

A solution in ethanol

有效期:

730

纯度:

≥98% (isomer mixture)