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16,16-dimethyl Prostaglandin E2
货号:14750-1 mg 规格:1 mg 目录价:¥1204
货号:14750-10 mg 规格:10 mg 目录价:¥10570
货号:14750-5 mg 规格:5 mg 目录价:¥5586
产品详情
产品名称:
16,16-dimethyl Prostaglandin E2
别名:
16,16-dimethyl PGE2
产品描述:
16,16-dimethyl PGE2 is a competitive inhibitor of 15-hydroxy PGDH, but it is not a substrate for the enzyme.{1789} Because of its resistance to metabolism by 15-hydroxy PGDH, it has a prolonged half-life in vivo. 16,16-dimethyl PGE2 acts as an agonist on most EP receptor subtypes, and has been used experimentally to induce cervical ripening, uterine contraction, and prevent ulceration of the gastric mucosa in rats and dogs.{437,1422} The Kd for activation of isolated EP2 receptors is about 1 nM.{1422} 16,16-dimethyl PGE2 can be used to preserve the self-renewal properties while preventing the differentiation of hematopoietic stem cells during expansion in culture.{27133,27095}
保存温度:
-20
运输温度:
-20
预期分子量:
380.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥95%
CAS号:
39746-25-3
分子式:
C22H36O5
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