20-ethyl Prostaglandin F2α-前列腺素-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳公海赌赌船官网登录网址科技有限公司

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20-ethyl Prostaglandin F2α

品牌：Cayman

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说明书

折扣/货期

货号：16940-1 mg	规格：1 mg	目录价：￥896
货号：16940-10 mg	规格：10 mg	目录价：￥6958
货号：16940-5 mg	规格：5 mg	目录价：￥3920

产品详情

产品名称:

20-ethyl Prostaglandin F2α

别名:

20-ethyl PGF2α|ICI 74205

产品描述:

20-ethyl Prostaglandin F2α (20-ethyl PGF2α) is an analog of PGF2α in which the ω-chain has been extended by the addition of two more methylene carbon atoms. It is therefore a modified version of the clinically approved glaucoma medication unoprostone.{8147} Unoprostone also contains lower side chain modifications (13,14-dihydro-15-keto) which severely limit its affinity for FP receptors, contributing to its lack of potency as a medication. 20-ethyl PGF2α retains the natural 15(S) allylic hydroxyl in the lower side chain, which may improve its potency as an intraocular hypotensive agent compared to unoprostone. The 2 carbon extension in 20-ethyl-PGF2α increases the Ki (120 nM) for the FP receptor from bovine corpus luteum only about 2.5-fold compared to PGF2α (50 nM).{11182} In vivo effects may be prolonged using 20-ethyl PGF2α, as the activity of 15-hydroxy PGDH using 20-ethyl PGF2α as a substrate is only 35% of the activity observed with PGF2α.{2309,11182}

保存温度:

-20

运输温度:

-20

预期分子量:

382.5

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥98%