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2,3-dinor-8-iso Prostaglandin F1α

品牌：Cayman

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说明书

折扣/货期

货号：15290-100 µg	规格：100 µg	目录价：￥4060
货号：15290-25 µg	规格：25 µg	目录价：￥1134
货号：15290-50 µg	规格：50 µg	目录价：￥2142

产品详情

产品名称:

2,3-dinor-8-iso Prostaglandin F1α

别名:

2,3-dinor-5,6-dihydro-15-F2t-IsoP|2,3-dinor-5,6-dihydro-15-F2t-Isoprostane|2,3-dinor-8-iso PGF1α|2,3-dinor-iPF1α-III

产品描述:

DMSO 2,3-dinor-8-iso Prostaglandin F1α (2,3-dinor-8-iso PGF1α) is an isoprostane and active metabolite of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) and the platelet aggregation inhibitor 8-iso PGF2α (Item No. 16350).{66406,3026} It is formed by the non-enzymatic, free radical peroxidation of arachidonic acid.{66406} 2,3-dinor-8-iso PGF1α induces vasoconstriction in isolated porcine retinal and brain microvessels (EC50s = 12.8 and 18.5 nM, respectively) but does not induce contraction of isolated rat aortic rings when used at a concentration of 31 µM.{66406,11221} It increases thromboxane B2 (TXB2; Item No. 19030) levels in isolated porcine brain slices when used at a concentration of 1 µM, an effect that can be reversed by the thromboxane A synthase inhibitor CGS 12970, the voltage-gated calcium channel inhibitor SKF 96365 (Item No. 10009312), or nicotinic acetylcholine receptor (nAChR) antagonist α-conotoxin.{66406}

保存温度:

-20

运输温度:

-20

预期分子量:

328.4

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥98%