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折扣/货期| 货号：REV-31-1110-MK-KI01 | 规格：1 Set | 目录价：￥9226 |
产品详情
产品名称:
5-Methylcytosine (5-mC) DNA Matched Antibody Pair
别名:
5-mC
产品描述:
5-Methylcytosine is a methylated form of the DNA base cytosine that regulates gene transcription and is involved in epigenetics. It is one of the best known epigenetic modifications. This methylation typically occurs at cytosine in CpG dinucleotides in vertebrates. When cytosine is methylated, the DNA maintains the same sequence, but the expression of methylated genes can be altered. 5-Methylcytosine is a very important repressor of transcription in the genome. When present in promoters, 5-Methylcytosine is associated with stable, long-term transcriptional silencing. This may occur by either blocking positive transcription factors, or promoting the binding of negative ones.
靶标/特异性:
This antibody pair detects 5-methylcytosine in denatured DNA (single strand DNA). It does not react to non-methylated cytosine and other modified cytosine (5-hmC, 5-caC, or 5-fC) in DNA. This product includes capture and detection antibodies for Sandwich ELISA assays.
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
检测方法:
Sandwich
促销活动
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