8-iso Prostaglandin F2α-d4-前列腺素-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳公海赌赌船官网登录网址科技有限公司

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8-iso Prostaglandin F2α-d4

品牌：Cayman

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说明书

折扣/货期

货号：316350-100 µg	规格：100 µg	目录价：￥8218
货号：316350-25 µg	规格：25 µg	目录价：￥2310
货号：316350-50 µg	规格：50 µg	目录价：￥4354

产品详情

产品名称:

8-iso Prostaglandin F2α-d4

别名:

15-F2t-Isoprostane-d4|8-epi PGF2α-d4|8-Isoprostane-d4|iPF2α-III-d4

产品描述:

8-iso PGF2α-d4 is intended for use as an internal standard for the quantification of 8-iso PGF2α by GC- or LC-mass spectrometry. 8-iso Prostaglandin F2α (8-iso PGF2α) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids.{320,371,855} It circulates in human plasma in two distinct forms - esterified in LDL phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2α level of about 150 pg/ml in normal volunteers. In normal human urine, 8-iso PGF2α levels are about 180-200 pg/mg of creatinine.{320,371} 8-iso PGF2α is a weak TP receptor agonist in vascular smooth muscle.{6640} Conversely, 8-iso PGF2α inhibits platelet aggregation induced by U-46619 (10−6 M) and I-BOP (3 x 10−7 M) with IC50 values of 1.6 x 10−6 M and 1.8 x 10−6 M, respectively.{855}

保存温度:

-20

运输温度:

-20

预期分子量:

358.5

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥99% deuterated forms (d1-d4)