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8-iso-15-keto Prostaglandin F2α
货号:16390-1 mg 规格:1 mg 目录价:¥2366
货号:16390-100 µg 规格:100 µg 目录价:¥448
货号:16390-500 µg 规格:500 µg 目录价:¥1302
产品详情
产品名称:
8-iso-15-keto Prostaglandin F2α
别名:
8-epi-15-keto PGF2α|8-iso-15-keto PGF2α
产品描述:
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation.{320} In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation.{6907} A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits.{11209} Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.{11221}
保存温度:
-20
运输温度:
-20
预期分子量:
352.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥95%
CAS号:
191919-01-4
分子式:
C20H32O5
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