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    Capsaicin
    货号:92350-100 mg 规格:100 mg 目录价:¥1204
    货号:92350-1 g 规格:1 g 目录价:¥5306
    货号:92350-250 mg 规格:250 mg 目录价:¥2520
    货号:92350-500 mg 规格:500 mg 目录价:¥3836
    产品详情
    产品名称:
    Capsaicin
    产品描述:
    Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities.{55276,55277,55278,55279} It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1; EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619.{55276} Capsaicin (10 and 50 µM) decreases LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production, as well as reduces LPS- and IFN-induced nitric oxide (NO) release in isolated mouse peritoneal macrophages.{55277} Capsaicin induces substance P (Item No. 24035) release in rat spinal cord slices with an EC50 value of 2.3 µM.{55278} It reduces acetylcholine- or phenylquinone-induced writhing (ED50s = 1.33 and 1.38 mg/kg, respectively, s.c.) but has no effect on the latency to paw withdrawal in the hot plate test in mice (ED50 = >20 mg/kg, s.c.).{55279} Formulations containing capsaicin have been used in the treatment of nerve pain associated with shingles.
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    305.4
    产品形式:
    A crystalline solid
    有效期:
    1460
    纯度:
    ≥95%
    来源:
    Plant/Capsicum
    CAS号:
    404-86-4
    分子式:
    C18H27NO3
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