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MMP12 ELISA Pair
货号:GTX500003 规格:1pair 目录价:¥4700
产品详情
产品名称:
MMP12 ELISA Pair
别名:
Matrix Metallopeptidase 12 , Hme , Me , Mme , Mmp-12 , Mmp12
反应种属:
Human
实验应用:
ELISA, Sandwich ELISA
同种型:
IgG
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
-20°C
产品形式:
Liquid
产地:
美国
功能与背景:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]
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