Nucleosome, Recombinant Human, H3K14ub1 dNuc, Biotinylated-突变/修饰核小体-ELISA_抗体_蛋白_核苷酸

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Nucleosome, Recombinant Human, H3K14ub1 dNuc, Biotinylated

品牌：EpiCypher

官网链接

说明书

折扣/货期

货号：16-0398

规格：25 µg

目录价：￥6300

产品详情

产品名称:

Nucleosome, Recombinant Human, H3K14ub1 dNuc, Biotinylated

产品描述:

H3K14ub1 designer mononucleosomes (dNucs) consist of 147 base pairs of DNA wrapped around an octamer core of histone proteins (two each of H2A, H2B, H3.1 and H4) to form a nucleosome, the basic repeating unit of chromatin. H3K14ub1 has been shown to promote the activity of the methyltransferase Clr4, which methylates H3K9, a known repressive mark [1]. The 147 bp 601 sequence, identified by Lowary & Widom [2], has high affinity for histone octamers and is useful for nucleosome assembly. The DNA in this nucleosome contains a 5’ biotin-TEG group. H3K14ub1 has a Cys to Ala substitution at position 110.

宿主来源:

Human

表达系统:

E. coli & synthetic DNA

保存温度:

Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.

运输温度:

Dry ice.

产品形式:

1.115 mg/mL mononucleosome in 22.6 µL 10 mM Tris HCl pH 7.5, 25 mM NaCl, 1 mM EDTA, 2 mM DTT, 20% glycerol. (14.4 µg protein, 25 µg DNA + protein)

产地:

美国