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    CD40L (human) (multimeric) (rec.)
    品牌: Adipogen
    产品货号: AG-40B-0010-C010
    规格: 10 ug

    报价:
    折后价:

    数量: - +
    产品详情
    * 以下信息仅供参考,详情请以原厂网站为准
    • 产品名称:
      CD40L (human) (multimeric) (rec.)
    • 别名:
      MultimericCD40L™; ACRP30headless:CD40L; ACRP30headless:CD154; ACRP30headless:TNFSF5; ADIPOQ-CD40L
    • 产品描述:
      MultimericCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations. MultimericCD40L™ has shown to suppress alum-induced IL-1beta release and caspase-1 activation in a dose-, CD40- and time dependent manner, without affecting BMDM viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators. The secretion of caspase-1 independent inflammatory mediators has been shown to be unaltered or even enhanced.
    • 反应种属:
    • 宿主来源:
      CHO cells
    • 实验应用:
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    • 产品浓度:
      0.1mg/ml after reconstitution
    • 表达系统:
    • 阳性对照:
    • 保存温度:
      -20°C
    • 运输温度:
      BLUE ICE
    • 细胞定位:
    • 预期分子量:
      ~35-40kDa (SDS-PAGE)
    • 产品形式:
      solid
    • 存储溶液:
      Lyophilized. Contains PBS
    • 有效期:
      Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    • 产地:
      瑞士
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    • 样本类型:
      Lyophilized. Contains PBS
    • 产品特点:
    • 纯度:
      >95% (SDS-PAGE)
    • 生物活性:
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