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Prostaglandin D Synthase (hematopoietic-type) Inhibitor I
货号:16256-1 mg 规格:1 mg 目录价:¥1694
货号:16256-10 mg 规格:10 mg 目录价:¥7602
货号:16256-5 mg 规格:5 mg 目录价:¥4228
产品详情
产品名称:
Prostaglandin D Synthase (hematopoietic-type) Inhibitor I
别名:
H-PGDS Inhibitor I
产品描述:
Prostaglandin D synthase (hematopoietic-type) (H-PGDS) inhibitor I is an inhibitor of H-PGDS (IC50 = 32 nM for the human enzyme).{28198} It is selective for H-PGDS over lipocalin-type PGDS, microsomal prostaglandin E synthase-1 (mPGES-1), COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = >10,000 nM for all). H-PGDS inhibitor I (1 or 10 mg/kg) inhibits PGD2 (Item No. 12010) production in vivo in rat spleen. It completely inhibits allergen-induced airway hyperresponsiveness in an ovine model of asthma.
保存温度:
-20
运输温度:
-20
预期分子量:
381.4
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1033836-12-2
分子式:
C19H19F4N3O
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