Prostaglandin E1-d4-前列腺素-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳公海赌赌船官网登录网址科技有限公司

首页产品中心前列腺素

Prostaglandin E1-d4

品牌：Cayman

官网链接

说明书

折扣/货期

货号：313010-100 µg	规格：100 µg	目录价：￥1960
货号：313010-50 µg	规格：50 µg	目录价：￥1092
货号：313010-500 µg	规格：500 µg	目录价：￥8148

产品详情

产品名称:

Prostaglandin E1-d4

别名:

Alprostadil-d4|PGE1-d4

产品描述:

Prostaglandin E1-d4 (PGE1-d4) is intended for use as an internal standard for the quantification of PGE1 (Item No. 13010) by GC- or LC-MS. PGE1 is a vasoactive prostaglandin and an active metabolite of dihomo-γ-linolenic acid (DGLA; Item No. 90230).{64886,10906} It is formed from DGLA by COX-1 and COX-2. PGE1 is an agonist of the PGE2 (Item No. 14010) receptor subtypes EP1, EP2, EP3, and EP4, and the IP receptor (Kis = 36, 10, 1.1, 2.1, and 33 nM, respectively, for the mouse receptors).{6640} It inhibits ADP-induced platelet aggregation of isolated human platelet-rich plasma (IC50 = 40 nM) and isoproterenol-induced increases in L-type calcium current (ICa) in isolated rabbit atrial cells (EC50 = 27 nM).{960,9061} PGE1 (100 nM) induces vasodilation in isolated rat aortic rings and activates ATP-sensitive potassium channels (KATP) in a cell-attached patch clamp assay using isolated rat vascular smooth muscle cells (VSMCs).{64886} It decreases femoral arterial perfusion pressure in dogs.{1350} Formulations containing PGE1 have been used in the treatment of erectile dysfunction and to maintain patency of the ductus arteriosesus in neonates with congenital heart defects who depend on a patent ductus arteriosesus for survival.

保存温度:

-20

运输温度:

-20

预期分子量:

358.5

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥99% deuterated forms (d1-d4)