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Prostaglandin E2 Ethanolamide

品牌：Cayman

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说明书

折扣/货期

货号：14012-1 mg	规格：1 mg	目录价：￥868
货号：14012-10 mg	规格：10 mg	目录价：￥6202
货号：14012-5 mg	规格：5 mg	目录价：￥3556
货号：14012-500 µg	规格：500 µg	目录价：￥462

产品详情

产品名称:

Prostaglandin E2 Ethanolamide

别名:

Dinoprostone Ethanolamide|PGE2-EA|Prostamide E2

产品描述:

Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 (Item No. 14010) with improved water solubility and stability. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA; Item No. 90050) and acts as an agonist at E prostanoid (EP) receptors 1-4 (Kis = 2.45, 0.46, 0.2, and 0.51 μM, respectively).{11045,10926} It also inhibits indoleamine 2,3-dioxygenase-1 (IDO-1) in THP-1 cells and human monocytes (IC50s = 5.7 and 4.7 μM, respectively).{40333} PGE2-EA (10 μM) prevents morphological changes and F-actin rearrangement as well as reduces L-homocysteine-induced NLRP3 inflammasome formation and activation in podocytes.{41626} Ex vivo, PGE2-EA reduces luminal damage and lymphocyte infiltration in a human mucosal explant colitis model.{41627}

保存温度:

-20

运输温度:

-20

预期分子量:

395.5

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥98%