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Prostaglandin F2α ethyl amide

品牌：Cayman

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说明书

折扣/货期

货号：16016-1 mg	规格：1 mg	目录价：￥756
货号：16016-10 mg	规格：10 mg	目录价：￥5740
货号：16016-5 mg	规格：5 mg	目录价：￥3234

产品详情

产品名称:

Prostaglandin F2α ethyl amide

别名:

Dinoprost ethyl amide|PGF2α-NEt

产品描述:

Prostaglandin F2α ethyl amide (PGF2α-NEt) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity.{8837} PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs.{8941} Although it has been claimed that PG ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 µg/g corneal tissue/hr.{8941,9311} PGF2α-NEt would be expected to show the typical intraocular effects of PGF2α free acid, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.

保存温度:

-20

运输温度:

-20

预期分子量:

381.6

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥98%