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13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
货号:9000406-1 mg 规格:1 mg 目录价:¥29008
货号:9000406-100 µg 规格:100 µg 目录价:¥3752
货号:9000406-25 µg 规格:25 µg 目录价:¥1064
货号:9000406-50 µg 规格:50 µg 目录价:¥1988
产品详情
产品名称:
13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
别名:
15-hydroxy Lubiprostone
产品描述:
PGE1 is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway. PGE1 inhibits platelet aggregation (IC50 = 40 nM) and increases vasodilation.{960,4165}13,14-dihydro-16,16-difluoro PGE1 is a biologically active metabolite of PGE1, inhibiting platelet aggregation with comparable potency to the parent compound.{2126,4165} The addition of two electron-withdrawing fluorine atoms, which should stabilize the molecule against hydrolytic cleavage, may be expected to delay degradation in vivo.{17623} 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro PGE1-3,3’,4,4’-d4) contains four deuterium atoms at the 3, 3’, 4, and 4’ positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1 by GC- or LC-mass spectrometry (MS).
保存温度:
-20
运输温度:
-20
预期分子量:
396.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥99% deuterated forms (d1-d4)
分子式:
C20H30D4F2O5
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