货号:16825-1 mg | 规格:1 mg | 目录价:¥1022 |
货号:16825-10 mg | 规格:10 mg | 目录价:¥8050 |
货号:16825-5 mg | 规格:5 mg | 目录价:¥4536 |
货号:16825-50 mg | 规格:50 mg | 目录价:¥35070 |
产品详情
产品名称:
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester
别名:
15(R)-17-phenyl trinor PGF2α isopropyl ester|15(R)-Bimatoprost isopropyl ester|15-epi Bimatoprost isopropyl ester
产品描述:
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.{9736} A 3 µg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.{9736}
保存温度:
-20
运输温度:
-20
预期分子量:
430.6
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥98%
CAS号:
130273-87-9
分子式:
C26H38O5
上一个:17-phenyl trinor Prostaglandin F2α isopropyl ester
下一个:13,14-dihydro-15-keto-tetranor Prostaglandin F1β
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