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anti-Acetylated-Lysine, Rabbit Monoclonal (RM101)
货号:REV-32-1012-00-C100 规格:100 µg 目录价:¥6090
产品详情
产品名称:
anti-Acetylated-Lysine, Rabbit Monoclonal (RM101)
别名:
Kac; AcK
产品描述:
Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. Post-translational acetylation occurs on the epsilon amino group of lysine residues as a reversible and highly dynamic post-translational modification (PTM) that is known to be a key regulator in multiple cellular events, including chromatin structure, transcription, metabolism, signal transduction and cytoskeletal regulation. The acetylation of lysine residues in proteins is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
宿主来源:
Rabbit
实验应用:
ELISA, FACS, ICC, IHC, IP, WB
靶标/特异性:
This antibody reacts to lysine-acetylated proteins. No cross reactivity with nonacetylated lysine, and lysine with other modification.
同种型:
Rabbit IgG
免疫原:
Acetyllysine -BSA.
克隆号:
RM101
产品浓度:
1 mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
纯度:
Protein A purified.
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