官网链接
折扣/货期| 货号：GTX500039 | 规格：1pair | 目录价：￥4700 |
产品详情
产品名称:
Cyclin D1 ELISA Pair
别名:
Cyclin D1 , Bcl1 , D11S287E , Prad1 , U21B31 , Ccnd1
反应种属:
Human
实验应用:
ELISA, Sandwich ELISA
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
-20°C
产品形式:
Liquid
产地:
美国
功能与背景:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq]
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