Human VEGF165 protein, His tag-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

首页产品中心细胞因子、趋化因子与生长因子

Human VEGF165 protein, His tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX67937-pro

规格：20μg

目录价：￥4100

产品详情

产品名称:

Human VEGF165 protein, His tag

别名:

vascular endothelial growth factor A , MVCD1 , VEGF , VPF

克隆号:

偶联:

Unconjugated

产品浓度:

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

Baculovirus

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

PBS, 30% Glycerol, 1mM DTT, 0.1mM PMSF, no preservative.

产地:

美国

功能与背景:

This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]

您可能感兴趣的产品

Human IL1F5 protein, His tag

货号：GTX68383-pro

Human VEGF165 protein, His tag

货号：GTX67937-pro

Rat IL6 protein, His tag (active)

货号：GTX67073-pro

Human IL6 protein, His tag (active)

货号：GTX67071-pro

Human IL2 protein (active)

货号：GTX67060-pro

Feline IL2 protein, His tag (active)