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IgE (human) Matched Antibody Pair

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1024-MK-KI01

规格：1 Set

目录价：￥7462

产品详情

产品名称:

IgE (human) Matched Antibody Pair

别名:

Immunoglobulin E

产品描述:

The Human IgE Matched Antibody Pairs is specific to Human IgE and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.Immunoglobulin E (IgE) is an antibody isotype that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains (Cepsilon1-Cepsilon4). IgE's main function is immunity to parasites such as helminths or certain protozoan parasites such as Plasmodium falciparum. IgE may have evolved as a last line of defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic reactions to drugs, bee stings and antigen preparations used in desensitization immunotherapy.

靶标/特异性:

The antibody pair detects only human IgE. It does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. There is no cross reactivity to any other immunoglobulins or IgG subclasses.

保存温度:

-20°C

运输温度:

BLUE ICE

有效期:

Stable for at least 1 year after receipt when stored at -20°C.

产地:

瑞士

检测方法:

Sandwich

样本类型:

Serum