LIN28A Antibody-单抗-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳公海赌赌船官网登录网址科技有限公司

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LIN28A Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F40207-0.08ML	规格：0.08 ml	目录价：￥2673.25
货号：F40207-0.4ML	规格：0.4 ml	目录价：￥5765.55

产品详情

产品名称:

LIN28A Antibody

产品描述:

LIN28A is a translational enhancer that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Suppressor of microRNA (miRNA) biogenesis, including that of let-7, miR107, miR-143 and miR-200c. Specifically binds miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in pre-miRNA terminal loop, and recruits ZCCHC11/TUT4 uridylyltransferase. This results in the terminal uridylation of target pre-miRNAs. Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation.[UniProt]

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, IHC, IF, ELISA

同种型:

Mouse IgG1, k

免疫原:

LIN28A recombinant protein was used to produce this monoclonal antibody.

克隆性:

Monoclonal (mouse origin)