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折扣/货期| 货号：CDX-M0170-M010 | 规格：10 mg | 目录价：￥896 |
产品详情
产品名称:
Magnolol
别名:
5,5'-Diallyl-2,2'-biphenyldiol; NSC 293099
产品描述:
Magnolol is a bioactive compound isolated from the bark of M. officinalis that has been used in Asian traditional medicine for the treatment of anxiety, sleep disorders, and allergic diseases. Magnolol is an antifungal, antibacterial and antioxidant compound. It demonstrates anti-inflammatory activity by interferring with NF-kappaB signalling and NLRP3 inhibition. Magnolol can activate cannabinoid (CB) receptors, behaving as a partial agonist with selectivity for the peripheral CB2 subtype versus central CB1. It been identified as modulators of the GABAA receptors in vitro. It is a potent antitumor and antiangiogenic compound. Shown to inhibit HIF-1alpha/VEGF signalling, inhibiting invasion and metastasis through MMP2/MMP9 and inhibiting microtubule polymerization. Induces apoptosis through EGFR/PI3K/Akt pathway. Shows anti-diabetic/anti-obesity activity targeting nuclear receptors retinoic X receptor alpha (RXRalpha) and peroxisome proliferator activated receptor gamma (PPARgamma). In addition promotes thermogenesis.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
266.33
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
528-43-8
分子式:
C18H18O2
溶解度:
Soluble in ethanol (1mg/ml), methanol (1mg/ml), DMSO (10mg/ml) or DMF (10mg/ml). Insoluble in water.
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