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Nucleosome, Recombinant Human, H3.1K27me3,S28phos, Biotinylated
品牌:EpiCypher
货号:16-0397 规格:50 µg 目录价:¥6900
产品详情
产品名称:
Nucleosome, Recombinant Human, H3.1K27me3,S28phos, Biotinylated
产品描述:
Recombinant mononucleosomes (H3.1K27me3,S28phos) consist of 147 base pairs of DNA wrapped around an octamer core of histone proteins (two each of H2A, H2B, H3.1, and H4) to form a nucleosome, the basic repeating unit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [1], has high affinity for histone octamers and is useful for nucleosome assembly. H3.1K27me3,S28phos contains trimethyl-lysine at position 27 and phosphoserine at position 28 on histone H3.1. The DNA contains a 5’ biotin-TEG group. H3S28 is an essential residue for modulating PRC2-mediated methylation at H3K27me3 [2].
宿主来源:
Human
表达系统:
E. coli & synthetic DNA
保存温度:
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws
运输温度:
Dry ice.
产品形式:
1.05 mg/mL mononucleosome in 47.6 µL 10 mM Tris HCl pH 7.5, 25 mM NaCl, 1 mM EDTA, 2 mM DTT, 20% glycerol. (27.4 µg protein, 50 µg DNA + protein)
产地:
美国
生产商:
EpiCypher
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