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折扣/货期| 货号：CDX-O0143-G001 | 规格：1 g | 目录价：￥1246 |
| 货号：CDX-O0143-G005 | 规格：5 g | 目录价：￥4970 |
产品详情
产品名称:
Olanzapine
别名:
2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine; LY-170053
产品描述:
Olanzapine is a 5-HT2 serotonin and D1/D2 dopamine receptor antagonist, that binds to dopamine D1, D2, and D4 receptors (Ki=31, 11, and 27 nM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C and 5-HT3 (Ki=4, 11, and 57 nM, respectively). It also binds to M1 muscarinic acetylcholine, alpha1-adrenergic and histamine H1 receptors (Ki=2, 19, and 7 nM, respectively). Olanzapine is an atypical antipsychotic that displays anticholinergic properties. Olanzapine shows antidepressant-like activity. Formulations containing olanzapine have been used in the treatment of schizophrenia and bipolar disorder and for the prevention and treatment of chronic nausea and chemotherapy-induced nausea and vomiting.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
312.43
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
132539-06-1
分子式:
C17H20N4S
溶解度:
Soluble in DMSO (10mg/ml) or DMF.
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