货号:CDX-P0260-M025 | 规格:25 mg | 目录价:¥546 |
货号:CDX-P0260-M100 | 规格:100 mg | 目录价:¥1414 |
货号:CDX-P0260-M250 | 规格:250 mg | 目录价:¥3374 |
产品详情
产品名称:
Paeoniflorin
别名:
NSC 178886
产品描述:
Paeoniflorin has diverse cellular actions, including modulating NMDA and TRPV1 receptors. It is reported to inhibit testosterone synthesis and stimulate aromatase activity. It also reduces inflammatory signaling by inhibiting p38 MAP kinase and blocks pancreatic cancer cell apoptosis by suppressing MMP-2/9 and ERK signaling. It has been described as an adenosine A1 receptor activator with neuroprotective and antidepressant effects, as well as hypoglycemic activity. It can activate adenosine A-1 receptors to increase the translocationss of PKC and GLUT4, two major signals for glucose uptake, from cytosol to membrane of the white adipocytes in rats. Recently it also was described as a liver X receptor (LXR) agonist, that can act as a ligand-activated transcription factor to exhibit antihyperlipidemic and neuroprotective effects. In addition, this potential anticancer agent, has ben described as a EP2 receptor agonists, a heat-shock protein (HSP)-inducing compound, by activation of HSF1, or by interacting with NOTCH1 or mTOR/HIF-1 signaling pathways.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
480.46
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at RT.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
23180-57-6
分子式:
C23H28O11
溶解度:
Soluble in DMSO, DMF, ethanol (all 20mg/ml) or water (10mg/ml).
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