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    Peanut Lectin (Biotin)
    货号:GTX01507 规格:1mg 目录价:¥1200
    产品详情
    产品名称:
    Peanut Lectin (Biotin)
    别名:
    Peanut Lectin , PNA , PNA lectin , Arachis hypogaea , Arachis hypogaea lectin , Peanut agglutinin lectin , Peanut agglutinin
    产品描述:
    Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosesides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells.
    实验应用:
    ELISA, IHC, WB
    靶标/特异性:
    Carbohydrate-Binding Specificity of Peanut Lectin : Galβ1, 3 GalNAc>>GalNAc>Gal
    克隆号:
    纯化方式:
    Purified by affinity chromatography followed by gel filtration chromatography
    偶联:
    Biotin
    产品浓度:
    5 mg/ml (Please refer to the vial label for the specific concentration.)
    表达系统:
    Native Protein
    保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
    运输温度:
    4°C
    产品形式:
    Liquid
    存储溶液:
    10mM Bicarbonate, 150mM NaCl, 0.1mM CaCl₂. Dilute in PBS, 0.1mM CaCl₂, 0.05% Sodium azide.
    产地:
    美国
    功能与背景:
    Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosesides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells. Peanut lectin contains one atom of Ca++ and Mg++ per unit.

    Inhibiting/Eluting sugars: 200 mM Galactose
    Carbohydrate-Binding Specificity of PNA: Galβ1, 3 GalNAc>>>>>GalNAc>Gal

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