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PTACH

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-P0063-M005	规格：5 mg	目录价：￥1680
货号：CDX-P0063-M025	规格：25 mg	目录价：￥6748

产品详情

产品名称:

PTACH

别名:

NCH 51; Cpd 51; S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate

产品描述:

Non-hydroxamate HDAC inhibitor (HDACi) (IC50: 32, 48 and 41nM for HDAC4, HDAC1 and HDAC6, respectively). Cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor. Predicted to exhibit a similar HDAC binding mode as that of SAHA, interacting with the active-site zinc targeting group. Shown to exhibit comparable antiproliferative and apoptotic activity as SAHA against various cancer cell lines. Inhibits growth of various cancer cells in vitro (EC50 = 1.1 - 9.1µM). Also reactivates latent HIV-1 gene expression.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

390.56

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at +4°C.